ceesdekker.net - An Overview
ceesdekker.net - An Overview
Blog Article
‘Of course, that's about appropriate. I look for a Bodily idea of biological techniques in a very base-up way. I believe you could possibly distinguish three lines of investigation in my team in the meanwhile. The main issues chromosome framework: How does one get a metre-extended DNA polymer folded and organised in this type of microscopic mobile? We have created visualisation tactics that make it possible for us to check how, by way of example, SMC proteins loop DNA (movie on Youtube) so that you can Develop up chromosomes.
You can assist our writer matching program! In case you observe any publications improperly attributed to this writer, remember to register and mark matches as appropriate or incorrect.
Throughout the very same time, the group of Paul McEuen, who was then based mostly within the University of California, Berkeley, showed equivalent final results on ropes of bundled nanotubes. With regards to the wrapping angle, nanotubes can can be found in metallic or semiconducting variants, a prediction that we and Charles Lieber’s group at Harvard University independently confirmed using scanning tunnelling spectroscopy experiments.
Sculpting nano-electrodes that has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial cell division; and initially at any time study on the dynamics DNA supercoils and the invention of supercoil hopping
Immediate immobilization of indigenous yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-film voltammetry
We form germs into sorts that deviate from their organic phenotype. Specifically, I'll show our capacity to shape Stay E. coli germs into novel designs like rectangles, squares, triangles and circles.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in gray, the rim of your pore is highlighted in red, as well as a 3D rendering with the movement of the DNA rod is displayed.
The rotors harness energy from the nanoscale water and ion movement that is produced by a static chemical or electrochemical prospective gradient while in the nanopore, which are recognized by way of a salt gradient or used voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological ailments, suggesting strategies to constructing Electricity-transducing motors at nanoscale interfaces.
Pretty cool, but that wasn’t truly in which my curiosity lay. I wished to pioneer And that i experienced the sensation which was no more doable, as the most attention-grabbing essential insights experienced already been uncovered. But my field had created several interesting new equipment to measure personal molecules. I decided that I desired to apply this to biology, to look at it from the Actual physical standpoint.’
perspective Share your interactive ePaper on all platforms and on your web site with our embed operate
Nanoscientist Cees Dekker is definitely an amiable and flamboyant gentleman who seems A lot young compared to the 62 yrs he actually is – trendy glasses, psychedelic shirt, participating smile – although not a person to waste time. He will take his time, but not more than important.
2008, 1st observation of protein-coated DNA translocation through nanopores; resolved the origin on the electrophoretic drive on DNA in nanopores; uncovered a big velocity increase of microtubules in electrical fields; identified ceesdekker.net an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid
2004, discovery of latest physics in translocation of DNA through nanopores; 1st experimental study of ions conduction in nanofluidic channels; initially electrochemistry with person one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; 1st electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization on the mechanical properties of double-stranded RNA; and very first one-molecule research of DNA translocation by a restriction-modification enzyme.